Award-winning writer and doctor Gavin Francis considers the transformations in mind and body that continue across the arc of human life. We can't avoid puberty, the menopause, or our hair turning grey. Others may be welcome milestones along our path - a much-wanted pregnancy, a cancer cured, or a long-awaited transition to another gender. We may find ourselves turning down dark paths, towards the cruel distortions of anorexia, or the shifting sands of memory loss. Francis draws on history, art, literature, myth and magic to show how the very essence of being human is change.